DREAM / The Prime Minister resigns and wakes up under the Parisian bridge!

 Kliko këtu për të tjera
Voxpress:

The key to eternal youth is revealed

2022-09-04 15:07:04Lifestyle SHKRUAR NGA REDAKSIA VOX
The key to eternal youth is revealed
The jellyfish

The jellyfish begins its life as larvae that wander about in the water until they find a rock support to anchor to. At this point metamorphosis occurs in polyps (not to be confused with octopuses), colonies of clones that rapidly reproduce asexually through budding. Each individual generates another close and identical to itself. The study is published in PNAS.

It is usually at this adult stage that the jellyfish ages and dies. But not Turritopsis dohrnii. When it is about to die, this jellyfish of a thousand springs abandons itself on the seabed and begins a strange decay. Its cells aggregate again into an amorphous mass, attach to a rocky substrate, and become polyps again, ready to transform into new jellyfish. It is a new beginning, a return to a stage of sexual immaturity.

This ability has been known since the late 1980s. But now Maria Pascual-Torner and her Spanish colleagues have looked to DNA for answers to the source of eternal youth. They sequenced that of Turritopsis dohrnii and compared it to that of a dying jellyfish Turritopsis rubra.

Duplicate genes associated with DNA repair and protection allow T. dohrnii to produce larger amounts of protective and "restructuring" proteins. Other special mutations allow the jellyfish to stop cell division and prevent the degradation of telomeres (the pieces of DNA found at the end of each chromosome that prevent the helix from winding down). Degeneration of telomeres is one of the reasons for aging metabolism of living beings.

But that's not all. During the metamorphosis that returns it to the polyp stage, the jellyfish T. dohrnii is able to silence genes involved in cellular maturation in order to return the cells to a primordial state and activate others that allow the cells of newborns to specialize again, when a new jellyfish detaches from the octopus.

Studying the equivalent genes in humans or mice can provide important information on aging and related diseases, such as cancer or neurodegenerative diseases.


Në përputhje me standarded JTI

Video

SHIKO KANALIN NE YOUTUBE
×