From various forms of cancer to cardiac and neurological disorders, there are 67 diseases that can be diagnosed thanks to a simple blood test, analyzing the proteins present in the plasma, according to a study by the University of Cambridge.
The study paves the way for a fast and simple diagnostic method in the future even for many rare diseases, which can currently take months or years to diagnose.
Thus, blood and the proteins circulating in it are confirmed as a mine of precious information.
Just a few months ago, two British studies were published which led to the discovery of 618 proteins present in the blood and indicators of 19 forms of cancer: 107 of these molecules can even signal danger for at least 7 years in advance.
Another work, published in December 2023 in Nature, was about the possibility of predicting, through a simple blood test, which organ will age first in apparently healthy individuals: this could allow treatment medical treatment should be sought even before the person becomes ill.
In this case, the researchers coordinated by Julia Carrasco-Zanini, Robert Scott and Claudia Langenberg analyzed data related to more than 3 thousand proteins obtained from a group of 40 thousand randomly selected individuals within the database sample of wide of "Biobank Britanica".
This is the largest study of proteomics, the discipline that analyzes all the proteins produced by an organism.
For each disorder, the study authors then identified the specific signature, consisting of the 5 to 20 most important proteins. The method obtained in this way proved to be more efficient in predicting the disease than those based on the standard information currently used.
"We are excited by the opportunity to identify new markers for screening and diagnosis among the thousands of proteins now measurable in human blood," says Claudia Langenberg, from the University of Cambridge.