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Japanese scientists are creating the drug that can grow new teeth for you

2026-05-04 19:46:00Lifestyle SHKRUAR NGA REDAKSIA VOX
The end of implants?

In Japan, biopharmaceutical company Toregem Biopharma, funded by Kyoto University, is developing a drug that could help people with tooth loss.

The path to this discovery began in 2007, when a team of scientists discovered that the lack of the USAG-1 gene in mice led to the development of extra teeth. This led the researchers to hypothesize that blocking the USAG-1 protein with a drug could activate tooth regeneration even in people with problems from birth or who had problems with tooth development.

Initially, the team tested antibodies against USAG-1 in mice and then developed humanized anti-USAG-1 antibodies, which showed success in stimulating tooth growth in mice and dogs.

According to reports from The Japan Times, the drug has also been tested on weasels, with similarly positive results.

Currently, the drug is entering the clinical trial phase in humans.

In the first phase, this year, it is being tested in healthy adults to assess its safety. In the next phase, it is expected to be tested in children between the ages of 2 and 6 who were born without some or all of their permanent teeth.

If these trials prove successful, the drug could be approved and used in dentistry worldwide in the future.


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