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The three-year study ends! Scientists discover the vegetable that saves you from clots and strokes

2024-03-12 11:22:46Lifestyle SHKRUAR NGA REDAKSIA VOX

The three-year study ends! Scientists discover the vegetable that saves you from

A three-year study, and the first of its kind worldwide by the Australian Heart Research Institute (HRI), has shown that a popular cruciferous vegetable can be protective against strokes, which are the leading cause of death and disability today.

Broccoli, as shown by preclinical findings published in ACS Central Science, contains a natural compound that prevents the formation of potentially threatening clots for ischemic stroke and also increases the effectiveness of antithrombotic drugs.

This is a revolutionary discovery that paves the way for the development of new, life-saving drugs, according to lead researcher Dr. Xuyu (Johnny) Liu, who explained the process of fibrinolysis: "When a patient suffers an ischemic stroke, they are given tissue plasminogen activator (tPA), a type of drug that breaks up the clot to slow the progression of blood clot damage. the brain. Unfortunately, it is successful only 20% of the time.'

60% more success

"We found in a preclinical trial that the success rate of tPA administration increases to 60% when the drug is administered with the broccoli-derived compound. Excitingly, this natural compound was not associated with symptoms of bleeding, a common side effect of taking anticoagulants that are controlled for the treatment of stroke. This means we could see paramedics treating ischemic stroke cases by administering a combined broccoli-based drug and tPA on the way to the hospital," said Dr Liu.

Initial trials have also shown that administration of the compound may delay the onset of stroke symptoms. "It can also be used prophylactically for patients at high risk of stroke," commented Dr. Liu.

The discovery of the beneficial ingredient in the vegetable was the work of 25-year-old PhD student Ivy Guan, who works in the research team led by Dr Liu. "Initially, I was attracted to the research subject because I have a strong interest in the use of natural products as medicines. "A lot of the research I do is very limited in the lab, but it's something that can go out into the world and impact people in their daily lives and encourage them to live healthier lives," he said.

The research team is now turning its attention to clinical trials, with the possibility that a new stroke prevention and anticoagulation treatment could be available within five years.

Dr. Liu believes the drug could have wider use in diseases related to blood clotting or clot formation.

"We are very excited to have isolated a natural compound that may have major beneficial effects. Our studies will continue to explore how highly purified vegetable components can benefit disease management. We want to understand how nature gives us gifts to improve our health. We have already discovered another compound from another vegetable that looks promising for thrombotic diseases," said Dr. Liu.


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