
Nail polish dryers can cause mutations that cause skin cancer and change DNA. A recent study published in "Nature Communications" by researchers at the University of California San Diego reached this conclusion.
They found that using these devices that emit ultraviolet (UV) rays can lead to cell death and cancer-causing mutations in human cells.
“If you look at the way these devices are presented, they are marketed as safe, nothing to worry about. But no one has studied these devices and how they affect human cells at the molecular and cellular levels until now," said Ludmil Alexandrov, professor of bioengineering, cellular and molecular medicine at UC San Diego and author of the study.
Using three different cell lines, adult human skin keratinocytes, human fibroblasts and mouse embryonic fibroblasts, the researchers found that using these beauty salon UV-emitting devices for just one 20-minute session led to cell death between 20 and 30 percent. While three successive exposures of 20 minutes caused the death of 65-70 percent of the exposed cells.
Exposure to UV light also caused mitochondrial and DNA damage in the remaining cells and resulted in mutations with patterns that can be seen in human skin cancer.
"We saw a lot of things. First, we saw that DNA is damaged. We also saw that some of the DNA damage is not repaired over time and this leads to mutations after each exposure to a UV gel nail dryer. Finally, we saw that exposure can cause mitochondrial dysfunction, which can also result in additional mutations. We looked at skin cancer patients and we see exactly the same patterns of mutations in these patients that were seen in the irradiated cells," said Alexandrov.
While the results show the harmful effects of using these devices on human cells, the researchers caution that a long-term epidemiological study is needed before definitively saying that using these machines leads to an increased risk of skin cancer. But the results of the study were clear: Chronic use of these nail polish drying machines is harmful to human cells.