Both drugs work differently to reduce pain. The main difference is that ibuprofen has anti-inflammatory effects, while paracetamol does not. Both medicines can be taken every four hours and are used to relieve pain and control fever. However, ibuprofen is more effective in relieving inflammation, making it a non-steroidal anti-inflammatory.
Inflammation occurs for a number of reasons: it can be a sign of infection or it is the body's reaction to the cause. It can be taken to relieve arthritis, period pain, back pain or toothache. The drug can also ease swelling caused by sprains and strains, although doctors say to try to wait at least 48 hours to avoid slowing the healing process.
The other major difference is that ibuprofen should never be taken on an empty stomach because it can irritate the mucous membranes and cause ulcers or bleeding. Ibuprofen is most effective when taken with or immediately after food.
Paracetamol does not need to be taken after food and can usually be taken safely with other medicines.
When should you not take ibuprofen and paracetamol together?
You should not give children ibuprofen and paracetamol together. Instead, doctors advise that if you find that the drug is not giving you relief, switch to the next pain reliever when it is next scheduled.
How long should you leave between taking paracetamol and ibuprofen?
For paracetamol, the usual dose for adults is one or two 500 mg tablets up to four times in 24 hours. You should always leave four hours between doses. For ibuprofen, the usual dose for adults is one or two 200 mg tablets three times a day. In some cases, the doctor may prescribe a higher dose of up to 600 mg to take four times a day if necessary.
If you take ibuprofen three times a day, leave at least six hours between doses. However, if you take it four times a day, leave at least four hours between doses. For those who have pain all the time, the doctor may recommend slow-release ibuprofen tablets. It is usual to take these once a day in the evening or twice a day, but leave 10 to 12 hours between doses if you are taking ibuprofen twice a day.
What happens if you take too much paracetamol and ibuprofen?
Taking too much ibuprofen can be really dangerous, so it's not worth doubling the dose if your pain is really bad. If you know you have overdosed then you should call your doctor immediately.