
Antibiotics are recommended by doctors to fight bad bacteria that endanger human health. But because of their powerful antimicrobial action, they also fight the good bacteria found in the human intestines.
As a result, antibiotics destroy the intestinal microbiome even after many years of consumption. It has even been seen that even a single course of antibiotics can have long-term effects.
At least that's what a study from Uppsala University in Sweden, published in Nature Medicine, suggests. Scientists wanted to study in more detail the effect of these essential drugs for treating serious infections, focusing on the bacterial community of the gut, known as the microbiome.
Previously, epidemiological studies have found links between excessive use of antibiotics and an increased risk of several diseases, such as type 2 diabetes and gastrointestinal infections.
The results of a Swedish university study show that some types of antibiotics can cause changes in the microbiome that last from 4 to 8 years after treatment. According to the authors of this study, it has been seen that even a course of just a few antibiotics can leave long-term traces in the gut microbiome.
Antibiotics are important in treating some serious infections, but they should always be taken as recommended by a doctor.
This study analyzed data on nearly 15,000 people, comparing the microbiome of those who had taken antibiotics and those who had not, and their effect also varies according to the type of antibiotic.
Stronger changes were seen with clindamycin, fluoroquinolones and flucloxacillin. While penicillin V, one of the most widely used antibiotics, had smaller and short-term effects.