DREAM / The Prime Minister resigns and wakes up under the Parisian bridge!

 Kliko këtu për të tjera
Voxpress:

A new vaccine for future pandemics?

2024-05-07 17:34:51Lifestyle SHKRUAR NGA REDAKSIA VOX
A new vaccine for future pandemics?
A new vaccine for future pandemics

While we have calmed down from Covid-19, scientists continue to work so that the next pandemic does not find us unprepared, writes focus.it.

A collaboration of researchers from the Universities of Cambridge, Oxford and Caltech has developed a vaccine technology that, in mice, has proven effective in protecting against a wide range of coronaviruses in our species.

The approach, described in a Nature Nanotechnology article, is part of a vaccine discipline called proactive prevention, which "proceeds" by designing immunization systems even before a pathogen presents itself, threatening public health.

Conventional vaccines include a single antigen (a substance foreign to the body capable of inducing a specific immune response), or instructions for its production, which stimulate the immune system to target a specific virus.

However, this approach, very effective for a single pathogen, does not protect against viruses of the same family that have not yet appeared and may have very different characteristics.

The technology presented in the study, called "Quartet Nanocage", introduces chains of different viral antigens into the body, united in a nanoparticle and held together by very strong chemical interactions, in a kind of "protein glue".

The different antigens train the immune system to attack specific regions shared by eight different coronaviruses – including SARS-CoV-2 and several other coronaviruses currently circulating in bats.

But the same vaccine-targeted regions also appear in many other related coronaviruses, including those not directly represented in the vaccine, as well as in pathogens not yet identified as dangerous to humans.

For example, the new vaccine candidate does not include antigens for SARS-CoV-1 (the SARS virus), but is still capable of producing an immune response against it in mice.

The new platform is simpler than many other proactive vaccination strategies being studied, which should speed the transition to human clinical trials.

Additionally, the same technology could be used to study vaccines against threats other than the coronavirus.


Në përputhje me standarded JTI

Video

SHIKO KANALIN NE YOUTUBE
×