
More than a billion people worldwide suffer from the unbearable pain of migraines, a neurological condition that can be accompanied by severe headaches and sensitivity to light and sound. But scientific research is bringing new treatments that offer hope for patients.
Megan Daniels, a 35-year-old lawyer from Liverpool, uses a neuromodulation device every day that stimulates nerves in her neck and head. “It’s very calming, it feels like waves are going through her brain,” she says. The device helps prevent attacks and reduces symptoms of vestibular migraine, which includes balance problems.
An important discovery has been the identification of CGRP molecules, which increase nerve sensitivity during attacks. Blocking them with special drugs has helped many patients, reducing the frequency of attacks by up to 75% in some cases. But the effects can be temporary, and some patients do not find complete relief.
Researchers are developing drugs that target other peptides, such as Pacap and orexin, which could be used as preventative treatments. These drugs not only stop existing attacks, but also reduce the chance of them coming back.
Botox, known for its cosmetic use, is effective in reducing chronic migraine attacks. Neuromodulation devices and electrodes that stimulate the nerves of the head and face are also showing promising results for patients who do not respond to medications.
Experts emphasize that treating migraines requires a comprehensive approach: a combination of medications, technological devices, lifestyle changes, psychological therapy, and attention to diet and physical activity. Megan Daniels emphasizes: No one thing completely solves migraines, all the pieces together form the health puzzle.